Detection of serum antinuclear antibodies in lymphoma patients

Detection of serum antinuclear antibodies in lymphoma patients.

We investigated the presence of serum antinuclear antibodies (ANAs) and autoantibodies and their relationship with serum prognostic indicators in lymphoma patients. The study population comprised 127 patients diagnosed with lymphoma and 138 healthy control subjects. The blood samples of the participants were assayed for ANAs by immunofluorescence, and autoantibodies were detected by western blo...

Serum Antinuclear Antibodies as Indicator of Relapse in Patients with Non-Hodgkin’s Lymphoma

Antinuclear antibodies (ANA) are antibodies that bind to several nuclear antigens. ANA have been reported in cancers, suggesting that they may have a role in the pathogenesis of malignancy [4,5]. Many studies have reported that NHL patients could display ANA antibodies [6,7]. This study assessed serum levels of ANA in NHL patients and examined its association with hematological, clinicopatholog...

Antinuclear antibodies in rosacea patients

INTRODUCTION Rosacea is a common inflammatory disorder, characterized by a spectrum of facial manifestations. The clinical similarity to other dermatoses, like lupus erythematosus, might lead to misdiagnosis, particularly in patients with elevated antinuclear antibody titers. AIM To assess the frequency, titer and specificity of antinuclear antibodies in rosacea patients and correlate these f...

Clinical utility of antinuclear antibodies : titrating the serum first.

Antinuclear Antibodies

knowledge of gene regulation, particularly in neoplastic cells, this deficit is striking. With our current understanding of chromosomal translocations, point mutations, and gene amplification in tumor cells, it is surprising to read that there is ". . . no difference between cancer and normal DNA . . ." (p. 130). The author spends a fair amount of time discussing possible mechanisms for the car...